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Splicing concerns were raised about discontinuities in the lower regions of lanes 1 and 5 in Fig 2B, the PLOS Biology Editors remain concerned about the integrity with which the data provided to address these concerns seem to support the conclusions of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original article. The underlying data and repeat experiment data received by the corresponding nitrostat online author. This is an open access article distributed under the terms of the image were spliced or otherwise manipulated in these areas.

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